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Serum pharmacokinetics of Cy5.5-labeled siRNA and nanoplexes. A semilogarithmic plot of serum concentration versus time for up to 2 h after intravenous injection of siRNA alone or in complex with the unmodified HK or modified RP-HK peptides. The data represent the mean ± SD of %ID/mL (n = 4 per carrier), where % ID/mL is the percentage of injected dose per milliliter of serum.
