Table 4.
Univariate and multivariate analysis of factors for detecting apex cancer among clinicopathological factors.
| True positive |
False negative | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| n = 65 | n = 53 | P value | 95% CI | ||
| Age, mean years | 65.2 | 65.3 | 0.898 | ||
| BMI, mean kg/m2 | 22.4 | 22.6 | 0.677 | ||
| PSA, mean ng/mL | 9.69 | 8.10 | 0.113 | ||
| F/T ratio, mean % | 12.8 | 16.4 | 0.024* | 0.953–1.100 | 0.737 |
| Prostate volume, mean mL | 32.1 | 32.5 | 0.890 | ||
| Clinical T stage | |||||
| T1c | 50 | 40 | |||
| T2a–c | 12 | 12 | 0.954 | ||
| ⩾T3a | 3 | 1 | |||
| Biopsy Gleason score | |||||
| 6 | 20 | 24 | |||
| 7 8 | 41 | 27 | 0.197 | ||
| 9 10 | 4 | 2 | |||
| Positive core number, mean | 3.66 | 2.43 | 0.0002* | 0.574–1.133 | 0.215 |
| pathological T stage | |||||
| T2a–c | 33 | 39 | 0.010 | 0.234–2.632 | 0.696 |
| ⩾T3a | 32 | 14 | |||
| RP apex Gleason score | |||||
| 6 | 13 | 13 | |||
| 7 8 | 46 | 35 | 0.431 | ||
| 9 10 | 6 | 5 | |||
| Apex tumor volume, mean mL | 0.802 | 0.193 | <0.0001* | 0.004–0.192 | 0.0002* |
| Total tumor volume, mean mL | 2.76 | 1.76 | 0.016* | 0.572–1.001 | 0.051 |
True positive: RP specimen positive and biopsy positive, false negative: RP specimen positive and biopsy negative, BMI: body mass index, PSA: prostate specific antigen, F/T: free total PSA ratio, RP: radical prostatectomy, *statistically significant.