Table 1.
| a: Housekeeping gene controls | ||
|---|---|---|
| Gene ID | House keeping genes | Fold change |
| ILMN_1802252 | GAPDH | 1.12103 |
| ILMN_2152131 | β-actin | 1.14968 |
| a Fibrous proteins collagens | ||||||
|---|---|---|---|---|---|---|
| Years after treatment | 1&2 | 1&2 | 10 | 10 | ||
| Gene ID | Gene Symbol | up | down | up | down | |
| ILMN_1751161 | COL7A1 | 8.5 | 4.0 | collagen, type VII, alpha 1 | ||
| ILMN_1792736 | COL21A1 | 4.6 | 5.1 | collagen, type XXI, alpha 1 | ||
| ILMN_1701308 | COL1A1 | 2.5 | collagen, type I, alpha 1 | |||
| ILMN_1789507 | COL11A1 | 2.5 | 2.8 | collagen, type XI, alpha 1 | ||
| ILMN_2311456 | COL11A2 | 2.3 | collagen, type XI, alpha 2 | |||
| ILMN_1685122 | COL9A2 | 2.4 | collagen, type IX, alpha 2 | |||
| ILMN_2370624 | COL13A1 | 2.4 | collagen, type XIII, alpha 1 | |||
| ILMN_1684554 | COL16A1 | 2.2 | collagen, type XVI, alpha 1 | |||
| ILMN_1788377 | COL27A1 | 2.2 | collagen, type XXVII, alpha 1 | |||
| ILMN_1733756 | COL12A1 | 2.2 | collagen, type XII, alpha 1 | |||
| ILMN_2402392 | COL8A1 | 2.1 | collagen, type VIII, alpha 1 | |||
| ILMN_1742534 | COL4A5 | 2.0 | 3.2 | collagen, type IV, alpha 5 | ||
| ILMN_1778308 | COL4A4 | 2.0 | 2.0 | collagen, type IV, alpha 4 | ||
| ILMN_1662731 | COL4A3 | 3.9 | collagen, type IV, alpha 3 | |||
| ILMN_1773079 | COL3A1 | 2.0 | 2.1 | collagen, type III, alpha 1 | ||
| ILMN_1651282 | COL17A1 | 2.0 | collagen, type XVII, alpha 1 | |||
| ILMN_1666665 | COL23A1 | 2.0 | collagen, type XXIII, alpha 1 | |||
| c: Matrix Metalloproteinases | ||||||
|---|---|---|---|---|---|---|
| Years after treatment |
1&2 | 1&2 | 10 | 10 | ||
| Gene ID | Gene Symbol |
up | down | up | down | |
| ILMN_1726448 | MMP1 | −4.3 | −3.2 | matrix metallopeptidase 1 (interstitial collagenase) | ||
| ILMN_1663873 | MMP13 | −2.9 | matrix metallopeptidase 13 (collagenase 3) | |||
| ILMN_1778333 | MMP24 | −5.7 | matrix metallopeptidase 24 (membrane-inserted) | |||
| ILMN_1796316 | MMP9 | −36.1 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | |||
| ILMN_1791796 | MMP16 | −2.0 | matrix metalloproteinase 16 (membrane-inserted) transcript variant 2, | |||
| ILMN_1784459 | MMP3 | −2.3 | −4.6 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) mRNA. | ||
| ILMN_1702361 | MMP16 | −2.3 | −8.1 | matrix metallopeptidase 16 (membrane-inserted) (MMP16), transcript variant 2, mRNA. | ||
| ILMN_2399016 | MMP28 | −2.4 | matrix metallopeptidase 28 (MMP28), transcript variant 3, | |||
| ILMN_1663873 | MMP13 | −2.9 | matrix metallopeptidase 13 (collagenase 3) | |||
| ILMN_1685917 | EMCN | −4.5 | endomucin (EMCN), | |||
| ILMN_2160015 | MMP21 | −2.7 | matrix metallopeptidase 21 | |||
| ILMN_1736026 | MMP8 | −2.7 | matrix metallopeptidase 8 (neutrophil collagenase) | |||
| ILMN_1718646 | MMP15 | −3.0 | matrix metallopeptidase 15 (membrane-inserted) | |||
| ILMN_2073758 | MMP12 | −5.3 | matrix metallopeptidase 12 (macrophage elastase) | |||
| ILMN_1786072 | MEPE | −10.8 | matrix extracellular phosphoglycoprotein | |||