Table 6.
Oxidative stress
| Years after treatment |
1&2 | 1&2 | 10 | 10 | ||
|---|---|---|---|---|---|---|
| Gene ID | Gene Symbol |
up | down | up | down | |
| ILMN_1730054 | GSTT1 | 48.1 | 51.7 | glutathione S-transferase theta 1 (GSTT1), | ||
| ILMN_2321150 | GSTTP2 | 4.6 | glutathione S-transferase theta pseudogene 2 (GSTTP2), non-coding RNA. XM_941198 XM_945014 XM_945016 | |||
| ILMN_2246548 | GSTTP2 | −4.2 | glutathione S-transferase theta pseudogene 2 (GSTTP2), non-coding RNA. XM_941198 XM_945014 XM_945016 | |||
| ILMN_1771964 | GSTA4 | 3.3 | glutathione S-transferase A4 (GSTA4), | |||
| ILMN_2218637 | GSTM1L | 2.9 | glutathione S-transferase M1-like (GSTM1L), non-coding RNA. | |||
| ILMN_1789418 | GSTT2 | 2.3 | glutathione S-transferase theta 2 (GSTT2), | |||
| ILMN_2246548 | GSTTP2 | −2.3 | glutathione S-transferase theta pseudogene 2 (GSTTP2), non-coding RNA. XM_941198 XM_945014 XM_945016 | |||
| ILMN_1716979 | GSTM4 | −2.9 | glutathione S-transferase M4 (GSTM4), transcript variant 1, | |||
| ILMN_1691430 | GSTCD | 2.2 | glutathione S-transferase, C-terminal domain containing (GSTCD), transcript variant 1, | |||
| ILMN_2168747 | GSTA2 | 4.9 | glutathione S-transferase A2 (GSTA2), | |||
| ILMN_1687387 | MGST1 | 4.4 | microsomal glutathione S-transferase 1 (MGST1), transcript variant 1d, | |||
| ILMN_1788122 | GSTA5 | −2.2 | glutathione S-transferase A5 (GSTA5), | |||
| ILMN_2227817 | GSTA3 | −5.8 | glutathione S-transferase A3 (GSTA3), | |||
| ILMN_1716979 | GSTM4 | −2.4 | glutathione S-transferase M4 (GSTM4), transcript variant 1, | |||
| ILMN_1789418 | GSTT2 | −4.7 | glutathione S-transferase theta 2 (GSTT2), | |||
| ILMN_1711642 | GSTZ1 | −8.8 | glutathione transferase zeta 1 (maleylacetoacetate isomerase) (GSTZ1), transcript variant 3, | |||
| ILMN_1776214 | TGM6 | −10.3 | transglutaminase 6 (TGM6), | |||
| ILMN_2193761 | LOC442245 | −3.0 | glutathione S-transferase M1 pseudogene (LOC442245), non-coding RNA. | |||
| ILMN_1668134 | GSTM1 | −3.7 | glutathione S-transferase M1 (GSTM1), transcript variant 1, | |||
| ILMN_1781952 | MGST1 | −3.6 | microsomal glutathione S-transferase 1 (MGST1), transcript variant 1b, | |||
| ILMN_1786847 | TGM3 | 6.0 | transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3), | |||
| ILMN_2127416 | GSR | −2.0 | glutathione reductase (GSR), | |||
| ILMN_1811489 | OXSR1 | 3.8 | 3.6 | oxidative-stress responsive 1 (OXSR1), | ||
| ILMN_2319588 | OSGIN1 | −3.5 | oxidative stress induced growth inhibitor 1 (OSGIN1), transcript variant 2, | |||
| ILMN_1686434 | TXNDC6 | −2.7 | thioredoxin domain containing 6 (TXNDC6), | |||
| ILMN_1731137 | TXNDC9 | 3.3 | thioredoxin domain containing 9 (TXNDC9), | |||
| ILMN_1654457 | TXN2 | 2.1 | thioredoxin 2 (TXN2), nuclear gene encoding mitochondrial protein, | |||
| ILMN_2188155 | TR2IT1 | −2.1 | thioredoxin reductase 2 intronic transcript 1 (TR2IT1), | |||
| ILMN_1799367 | TXNDC14 | 4.5 | 4.4 | thioredoxin domain containing 14 (TXNDC14), | ||
| ILMN_1717056 | TXNRD1 | −3.0 | thioredoxin reductase 1 (TXNRD1), transcript variant 5, | |||
| ILMN_2258268 | GLRX2 | −13.1 | glutaredoxin 2 (GLRX2), transcript variant 2, | |||
| ILMN_2222234 | PRDX4 | 3.4 | peroxiredoxin 4 (PRDX4), | |||
| ILMN_2395969 | PRDX3 | −2.1 | peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, transcript variant 1, | |||
| ILMN_1775871 | GPX5 | −5.6 | glutathione peroxidase 5 (epididymal androgen-related protein) (GPX5), transcript variant 1, | |||
| ILMN_2385410 | GPX5 | −10.4 | glutathione peroxidase 5 (epididymal androgen-related protein) (GPX5), transcript variant 1, | |||
| ILMN_2133205 | GPX2 | −15.3 | glutathione peroxidase 2 (gastrointestinal) (GPX2), | |||
| ILMN_1802706 | IDH3G | 7.3 | isocitrate dehydrogenase 3 (NAD+) gamma (IDH3G), nuclear gene encoding mitochondrial protein, transcript variant 2, | |||
| ILMN_2363880 | ALDH3B2 | 5.7 | aldehyde dehydrogenase 3 family, member B2 (ALDH3B2), transcript variant 2, | |||
| ILMN_1677637 | BDH1 | 5.0 | 3-hydroxybutyrate dehydrogenase, type 1 (BDH1), nuclear gene encoding mitochondrial protein, transcript variant 2, | |||
| ILMN_1679178 | ATP5D | 10.0 | ATP synthase, H+ transporting, mitochondrial F1complex, delta subunit (ATP5D), nuclear gene encoding mitochondrial protein, transcript variant 1, | |||
| ILMN_1791754 | CPT1B | 10.0 | carnitine palmitoyltransferase 1B (muscle) (CPT1B), nuclear gene encoding mitochondrial protein, transcript variant 3, | |||
| ILMN_1685703 | ACOX2 | 8.5 | acyl-Coenzyme A oxidase 2, branched chain (ACOX2), | |||
| ILMN_1654118 | BCL2L1 | 8.1 | BCL2-like 1 (BCL2L1), nuclear gene encoding mitochondrial protein, transcript variant 1, | |||
| ILMN_2198408 | MFF | 8.0 | mitochondrial fission factor (MFF), nuclear gene encoding mitochondrial protein, | |||
| ILMN_2042343 | MRPL42P5 | 6.1 | mitochondrial ribosomal protein L42 pseudogene 5 (MRPL42P5), non-coding RNA. | |||
| ILMN_1700168 | LARS2 | 4.1 | leucyl-tRNA synthetase 2, mitochondrial (LARS2), nuclear gene encoding mitochondrial protein, | |||
| ILMN_1778187 | TARS2 | 3.0 | threonyl-tRNA synthetase 2, mitochondrial (putative) (TARS2), nuclear gene encoding mitochondrial protein, | |||
| ILMN_1733562 | TFB1M | 2.7 | transcription factor B1, mitochondrial (TFB1M), | |||
| ILMN_1695472 | MRPL10 | 2.6 | mitochondrial ribosomal protein L10 (MRPL10), nuclear gene encoding mitochondrial protein, transcript variant 2, | |||
| ILMN_1727390 | ATPAF2 | 2.5 | ATP synthase mitochondrial F1 complex assembly factor 2 (ATPAF2), nuclear gene encoding mitochondrial protein, | |||
| ILMN_1752099 | CYP11B2 | −3.1 | cytochrome P450, family 11, subfamily B, polypeptide 2 (CYP11B2), nuclear gene encoding mitochondrial protein, |