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The analysis of a representative microarray experiment is shown as a scatter-plot in the top row. It demonstrates that very few genes are differentially expressed in early AD (no fold-change >2). mRNA expression of three genes of interest was further validated using qRT-PCR: ALAS2, CTR1 and FOS. No significant difference in mRNA expression was found for any of the three genes evaluated. (For n see Table 1).
