Table S3.
Nodes from the regulation of CDKN2A expression submodel of the DACS Network that are predicted as HYPs by RCR on the GSE28464 test data set.
| Regulation of CDKN2A HYPs | Expected Direction | Test Data set |
|---|---|---|
| GSE28464 | ||
| Predicted in consistent directions | ||
| CDKN2A | ||
| ETS1 | ||
| ETS2 | ||
| HBP1 | ||
| PPARG | ||
| SMARCB1 | ||
| SP1 | ||
| taof(ETS2) | ||
| taof(PPARG) | ||
| taof(YY1) | ||
| YY1 | ||
| BMI1 | ||
| EED | ||
| EZH2 | ||
| GLI2 | ||
| HDAC3 | ||
| taof(GLI2) | ||
Notes: Expected direction is based on internal causality of the regulation of CDKN2A expression submodel. Yellow = predicted increase in abundance or activity, blue = predicted decrease in abundance or activity. Submodel nodes that are shared with other senescence models are bolded.
Abbreviation: taof(X), transcriptional activity of X.