Table 1.
LOD scores for markers on chromosome 10p11.21-q21.1 in two USH1K families
| Marker | cMa | Mbb | Maximum Two-point LOD scores (θ) | |
|---|---|---|---|---|
|
| ||||
| PKDF231 | PKDF608 | |||
| D10S197 | 52.10 | 26,526,881 | - | 0.66 (.30) |
| D10S213 | 57.42 | 29,473,069 | 2.52 (.05) | 0.38 (.20) |
| D10S208 | 60.64 | 31,680,077 | - | - |
| D10S1780 | 63.83 | 35,889,684 | 2.46 (.05) | 1.46 (.10) |
| D10S578 | 65.97 | 37,042,086 | 0.64 (.20) | 3.21 (0) |
| D10S1233 | 66.50 | 44,729,498 | 3.15 (0) | - |
| D10S196 | 70.23 | 52,142,268 | 1.98 (0) | 0.92 (0) |
| D10S220 | 70.23 | 52,347,295 | 3.74 (0) | - |
| D10S539 | 72.90 | 55,060,405 | 4.15 (0) | 3.83 (0) |
| D10S1790 | 75.57 | 55,205,311 | 1.89 (.10) | - |
| D10S1643 | 74.50 | 55,271,473 | 1.69 (0) | - |
| D10S546* | 75.57 | 56,094,398 | 0.15 (.25) | 0.65 (0) |
| D10S1652 | 80.77 | 64,407,495 | - | 1.66 (.05) |
| D10S581 | 82.50 | 65,849,304 | - | 0.35 (.20) |
a
The sex averaged genetic map positions in centiMorgans (cM) are taken from the Marshfield human genetic map (http://research.marshfieldclinic.org/genetics).
b
Physical map positions in megabases (Mb) are according to February 2009 human reference sequence GRCh37, hg19.
*
PCDH15 intronic STR marker.