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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Atherosclerosis. 2012 Feb 2;222(1):138–147. doi: 10.1016/j.atherosclerosis.2012.01.039

Table 3B.

Candidate gene SNP associations for PAD (ABI < 0.9): discovery meta-analysis, p < 10−4. African Americans, n = 7267.

SNP Chr Physical position Nearest gene Feature Major/minor allele MAFa Odds ratio 95% CI p Value phetb
rs4987756 18 59,060,091 BCL2 Intron A/G 0.01 2.99 1.88, 4.76 3.78×10−6 0.63
rs1256143 14 63,981,380 MTHFD1 Intron C/T 0.19 1.72 1.21, 1.66 1.43×10−5 0.05
rs13004470 2 242,159,756 BOK Intron C/T 0.18 1.39 1.19, 1.62 4.69×10−5 0.81
rs9830448 3 154,349,978 RAPB2 Locus region C/A 0.07 1.58 1.28, 2.02 4.79×10−5 0.73
a

MAF = minor allele frequency.

b

p-for-heterogeneity by Cochran’s Q.