Table 2.
Na (mmol/kg Hb) | K (mmol/kg Hb) | Mg (mmol/kg Hb) | s[Na+] (mM) | s[K+] (mM) | s[Mg2+] (mg/dL) | Ouab.-sens Na efflux | Bumet.-sens Na efflux | |
---|---|---|---|---|---|---|---|---|
(mmol/1013cellsxhr) | (mmol/1013cellsxhr) | |||||||
III.2 | 542 | 24.8 | 10.2 | 144 | 5.0 | 1.9 | 0.11 | 0.00 |
IV.1 | 312 | 16.9 | 6.8 | 144 | 4.6 | 2.5 | 0.00* | 0.00* |
IV.2 | 322 | 13.3 | 6.7 | 143 | 4.0 | 2.2 | 0.00* | 0.00* |
IV.3 | 554 | 23.5 | 9.0 | 141 | 4.5 | 2.3 | 0.00 | 0.14 |
IV.4 | 431 | 18.9 | 8.0 | 144 | 4.2 | 1.9 | 0.29 | 0.32 |
V.1 | 515 | 33.3 | 10.2 | 139 | 5.2 | NA | 0.00* | 0.00* |
V.2 | 387 | 28.3 | 8.7 | 145 | 5.4 | NA | NA | NA |
Cell contents of Na, K, and Mg were determined by atomic absorption on cells shipped overnight to Boston. Serum electrolytes (s [Na+] and s[K+]) were measured by ion selective electrodes in serum prepared from fresh blood (see Methods). Values of cell ion content and serum electrolyte concentrations are means of two triplicate determinations except for V.1 and V.2 (n=1). For Na efflux values without *, n=2 triplicate determinations; with *, n=1 triplicate determination.
NA, not available. Data from unaffected dogs is shaded.