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. 2013 Mar 13;8(3):e59059. doi: 10.1371/journal.pone.0059059

Table 1. Covariance model selected with the Akaïke criterion to identify the determinants of mRNA stability.

Selected parameter Coefficient estimate Standard error p-value
[mRNA] −0.065 0.019 8.10E−4
Length −0.059 0.013 9.65E−6
ΔG| 0.030 0.012 1.56E−2
CAI 0.029 0.015 4.73E−2
Functional category
AMI −0.095 0.068 1.65E−1
CEL −0.108 0.071 1.28E−1
COF −0.067 0.072 3.50E−1
ENV −0.121 0.057 3.50E−2
FAT −0.143 0.090 1.10E−1
INT 0.202 0.105 5.51E−2
NRJ 0.087 0.044 4.67E−2
OTH 0.023 0.057 6.93E−1
PUR 0.082 0.062 1.81E−1
REG −0.108 0.044 1.40E−2
REP 0.035 0.066 5.96E−1
TRD 0.108 0.047 2.06E−2
TRS 0.044 0.079 5.68E−1
TSP 0.082 0.041 4.40E−2
Growth rate
0.11 h−1 0.763 0.023 <2.00E−16
0.51 h−1 0.189 0.018 <2.00E−16
0.80 h−1 −0.952 0.025 <2.00E−16

Light gray parameters were selected by the model but the confidence for their estimated coefficients is not sufficiently high to be considered as significant (p-value>0.05).

AMI = Amino acid biosynthesis, CEL = cellular process, COF = biosynthesis of cofactors, ENV = cell envelope, FAT = fatty acids metabolism, INT = central intermediary metabolism, NRJ = energy metabolism, OTH = other categories, PUR = purines, pyrimidines, nucleosides and nucleotides, REG = regulatory functions, REP = replication, TRD = translation, TRS = transcription, TSP = transport and binding proteins.