Table 1. Covariance model selected with the Akaïke criterion to identify the determinants of mRNA stability.
Selected parameter | Coefficient estimate | Standard error | p-value |
[mRNA] | −0.065 | 0.019 | 8.10E−4 |
Length | −0.059 | 0.013 | 9.65E−6 |
ΔG| | 0.030 | 0.012 | 1.56E−2 |
CAI | 0.029 | 0.015 | 4.73E−2 |
Functional category | |||
AMI | −0.095 | 0.068 | 1.65E−1 |
CEL | −0.108 | 0.071 | 1.28E−1 |
COF | −0.067 | 0.072 | 3.50E−1 |
ENV | −0.121 | 0.057 | 3.50E−2 |
FAT | −0.143 | 0.090 | 1.10E−1 |
INT | 0.202 | 0.105 | 5.51E−2 |
NRJ | 0.087 | 0.044 | 4.67E−2 |
OTH | 0.023 | 0.057 | 6.93E−1 |
PUR | 0.082 | 0.062 | 1.81E−1 |
REG | −0.108 | 0.044 | 1.40E−2 |
REP | 0.035 | 0.066 | 5.96E−1 |
TRD | 0.108 | 0.047 | 2.06E−2 |
TRS | 0.044 | 0.079 | 5.68E−1 |
TSP | 0.082 | 0.041 | 4.40E−2 |
Growth rate | |||
0.11 h−1 | 0.763 | 0.023 | <2.00E−16 |
0.51 h−1 | 0.189 | 0.018 | <2.00E−16 |
0.80 h−1 | −0.952 | 0.025 | <2.00E−16 |
Light gray parameters were selected by the model but the confidence for their estimated coefficients is not sufficiently high to be considered as significant (p-value>0.05).
AMI = Amino acid biosynthesis, CEL = cellular process, COF = biosynthesis of cofactors, ENV = cell envelope, FAT = fatty acids metabolism, INT = central intermediary metabolism, NRJ = energy metabolism, OTH = other categories, PUR = purines, pyrimidines, nucleosides and nucleotides, REG = regulatory functions, REP = replication, TRD = translation, TRS = transcription, TSP = transport and binding proteins.