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. 2013 Mar 13;8(3):e59059. doi: 10.1371/journal.pone.0059059

Table 2. Main mechanisms controlling mRNA concentrations.

Compared cultures Mainly transcriptional control ρD ≤0 Shared control 0<ρD<1 Mainly degradation control ρD ≥1
Number of genes Percentage of the total Number of genes Percentage of the total Number of genes Percentage of the total
Chemostat 0.80 vs. 0.51 h−1 479 98% 4 1% 4 1%
0.51 vs. 0.11 h−1 454 84% 75 14% 14 3%
Batch Exponential phase (0.8 h−1) vs. deceleration (0.38 h−1) 452 72% 109 17% 67 11%
Deceleration (0.38 h−1) vs. stationary (0.04 h−1) 490 77% 66 10% 77 12%

vs. indicates the growth conditions considered for the calculation of the regulation coefficients. Chemostat and batch indicate that RNA half-lives were determined in continuous or discontinuous cultures, respectively. In chemostat cultures, cells were at a steady state, with growth limited by the isoleucine concentrations. In batch cultures, isoleucine in the medium was progressively consumed (until starvation was reached) and the cells were in a dynamic process of adaptation.