Table 4. Hospitalization, intensive care unit utilization, and mortality comparison between hemodialysis patients with and without influenza vaccination.

	Vaccine			Non-vaccine
Outcome	Event	PY	Rate#	Event	PY	Rate#	IRR*(95% CI)	Adjusted IRR (95% CI)	Adjusted HR (95% CI)
Pneumonia/influenza†	139	620	22.4	445	2584	17.2	1.30(1.08, 1.56)	0.77(0.64, 0.93)	0.78(0.64, 0.96)
Septicemia, bacteremia, and viremia†	103	637	16.2	347	2661	13.0	1.24(1.02, 1.50)	0.66(0.47, 0.92)	0.72(0.56, 0.88)
Heart disease†	341	522	65.3	1138	2203	51.7	1.26(1.08, 1.47)	0.83(0.71, 0.97)	0.85(0.75, 0.96)
Respiratory Failure†	66	653	10.1	262	2697	9.7	1.04(0.84, 1.29)	0.52(0.42, 0.64)	0.53(0.41, 0.70)
Intensive care unit admission†	17	660	2.6	184	2696	6.8	0.38(0.27, 0.53)	0.19(0.14, 0.27)	0.20(0.12, 0.33)
Mortality†	123	665	18.5	581	2765	21.0	0.88(0.73, 1.07)	0.49(0.41, 0.59)	0.50(0.41, 0.60)

Rate^#, incidence rate, per 100 person-years; IRR^*, incidence rate ratio

Hospitalization^†: adjusted for age, CAD, CHF, cancer, COPD, stroke, and calendar year

Hospitalization for pneumonia/influenza^†: adjusted for age, sex, CAD, CHF, cancer, diabetes, atrial fibrillation, COPD, and calendar year

Hospitalization for septicemia, bacteremia, and viremia^†: adjusted for age, cancer, diabetes, atrial fibrillation, and calendar year

Hospitalization for heart disease^†: adjusted for age, CAD, CHF, hypertension, diabetes, atrial fibrillation, chronic hepatitis, and calendar year

Respiratory Failure^†: adjusted for age, sex, CAD, cancer, CHF, diabetes, hypertension, chronic hepatitis, and calendar year

Intensive care unit^†: adjusted for age, cancer, hyperlipidemia, hypertension, diabetes, atrial fibrillation, chronic hepatitis, and calendar year

Mortality^†: adjusted for age, sex, CAD, cancer, CHF, diabetes, hyperlipidemia, hypertension, chronic hepatitis, atrial fibrillation, COPD, and calendar year