Table 1.
Behavioral, biochemical and subjective measures for the experimental group presented by period, day and cigarette. Values are adjusted means and standard errors.
| OWN BRAND | CRUSH | NON-CRUSH | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study Day | 1 | 1 | 5 | 5 | 10 | 10 | 15 | 15 | 20 | 20 | 25 | 25 | 30 | 30 | 35 |
| Cigarette | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| Biomarkers | |||||||||||||||
| CO session start (ppm) | 26.8 (2.8) | 25.3 (2.2) | 22.3 (1.9) | 23.3 (2.2) | 23.5 (1.9) | 23.5 (2.2) | 22.9 (2.4) | 23.4 (2.4) | |||||||
| CO boost (ppm) | 6.2 (0.8) | 5.9 (0.8) | 5.9 (0.5) | 4.6 (0.5) | 4.0 (0.7) | 3.9 (0.8) | 4.1 (0.5) | 4.3 (0.5) | 3.7 (0.5) | 3.2 (0.6) | 3.7 (0.7) | 3.8 (0.6) | 3.5 (0.5) | 4.6 (0.5) | 3.9 (0.5) |
| Nicotine (ug/ml) | 1.706 (0.30) | 2.68 (0.54) | 2.49 (0.43) | ||||||||||||
| Cotinine (ug/ml) | 4.00 (0.74) | 4.46 (0.69) | 3.74 (0.39) | ||||||||||||
| 8-Oxo-dGuo (ng/ml) | 3.52 (0.46) | 5.10 (1.00) | 4.52 (0.94) | ||||||||||||
| Smoking Topography | |||||||||||||||
| Total Puff Volume (ml) | 612.6 (74.6) | 517.9 (36.8) | 560.7 (42.7) | 600.4 (42.0) | 586.0 (42.1) | 630.7 (42.7) | 601.6 (41.0) | 614.3 (46.3) | 650.3 (47.9) | 664.4 (56.8) | 738.3 (50.4) | 648.7 (48.3) | 623.6 (57.5) | 658.0 (47.4) | 677.9 (57.1) |
| Number of Puffs | 11.2 (0.6) | 11.1 (0.8) | 12.6 (0.7) | 12.2 (0.7) | 11.9 (0.8) | 12.0 (0.6) | 12.4 (0.7) | 12.0 (0.8) | 12.0 (0.9) | 12.4 (1.2) | 13.3 (1.1) | 12.2 (0.9) | 10.9 (1.0) | 12.1 (0.7) | 12.7 (1.0) |
| Puff Duration (s) | 1.7 (0.1) | 1.7 (0.1) | 1.6 (0.1) | 1.7 (0.1) | 1.5 (0.1) | 1.6 (0.1) | 1.6 (0.1) | 1.6 (0.1) | 1.7 (0.2) | 1.8 (0.2) | 1.7 (0.1) | 1.8 (0.2) | 1.9 (0.2) | 1.7 (0.1) | 1.8 (0.1) |
| Interpuff Interval (s) | 30.1 (2.1) | 33.7 (3.2) | 31.4 (3.0) | 30.6 (3.0) | 32.5 (3.9) | 31.5 (2.6) | 29.4 (2.8) | 30.7 (3.2) | 34.4 (2.9) | 36.4 (4.0) | 29.8 (3.5) | 28.2 (2.9) | 31.6 (3.1) | 29.9 (3.1) | 29.4 (3.4) |
| Subjective Ratings | |||||||||||||||
| Strength: (very weak/very strong) | 61.2 (5.6) | 66.4 (5.5) | 65.2 (4.9) | 57.5 (6.3) | 65.9 (5.5) | 66.0 (5.1) | 63.5 (4.8) | 65.8 (5.1) | 63.8 (5.7) | 46.4 (6.5) | 50.8 (4.6) | 55.5 (4.7) | 51.7 (5.2) | 59.1 (4.5) | 53.3 (5.1) |
| Harshness: (very mild/very harsh) | 42.5 (6.0) | 38.3 (5.9) | 43.4 (5.4) | 49.3 (5.3) | 51.6 (6.1) | 50.8 (6.7) | 49.7 (5.8) | 48.1 (5.9) | 46.0 (5.4) | 50.1 (6.7) | 43.5 (5.4) | 50.5 (5.2) | 42.5 (5.9) | 45.9 (5.4) | 45.4 (5.5) |
| Heat: (no heat/very hot) | 21.4 (5.3) | 21.7 (4.5) | 33.5 (6.0) | 38.3 (6.1) | 29.6 (5.5) | 34.5 (6.3) | 37.9 (6.7) | 41.2 (6.4) | 35.7 (6.4) | 31.5 (6.4) | 34.0 (5.7) | 30.0 (4.9) | 29.2 (4.7) | 36.6 (5.8) | 34.5 (5.1) |
| Draw: (easy/difficult) | 25.6 (5.6) | 26.0 (5.4) | 34.5 (5.6) | 32.5 (6.2) | 19.2 (4.1) | 26.8 (4.7) | 25.4 (5.1) | 26.5 (5.0) | 20.2 (4.2) | 33.6 (5.9) | 28.5 (5.7) | 26.8 (5.4) | 27.4 (5.7) | 31.5 (5.8) | 22.6 (4.7) |
| Taste: (very bad/very good) | 56.6 (5.8) | 61.3 (5.3) | 57.6 (4.9) | 49.6 (6.4) | 49.3 (6.0) | 47.3 (6.0) | 51.0 (5.1) | 48.2 (6.2) | 52.3 (5.8) | 29.3 (5.1) | 37.5 (5.6) | 38.9 (5.3) | 40.0 (5.4) | 40.4 (5.9) | 39.0 (5.7) |
| Satisfaction from smoking: (unsatisfying/satisfying) | 55.5 (6.2) | 54.5 (6.7) | 56.0 (6.0) | 51.0 (5.9) | 51.2 (6.3) | 48.8 (6.2) | 49.5 (6.5) | 54.9 (6.3) | 54.5 (6.6) | 35.7 (5.1) | 44.0 (5.6) | 42.2 (5.9) | 46.9 (5.7) | 45.6 (5.9) | 44.8 (5.6) |
| (Burned/Did not burn) too fast in too few puffs | 54.0 (5.7) | 53.1 (5.1) | 60.1 (5.8) | 61.1 (5.7) | 56.1 (6.5) | 64.5 (6.1) | 66.0 (5.9) | 71.0 (5.9) | 65.0 (6.4) | 60.7 (6.4) | 66.5 (5.9) | 65.6 (6.5) | 63.8 (6.5) | 67.0 (6.5) | 69.8 (6.2) |
| Mild taste/Not mild taste | 42.0 (6.1) | 52.3 (6.0) | 45.9 (5.9) | 49.6 (6.6) | 54.9 (7.0) | 53.5 (6.4) | 50.5 (5.9) | 56.2 (5.7) | 47.3 (6.2) | 51.2 (6.6) | 50.7 (5.0) | 45.3 (5.2) | 50.7 (5.1) | 49.9 (5.2) | 46.1 (5.9) |
| It (was/was not) too mild for me | 69.4 (5.1) | 66.7 (6.1) | 68.2 (6.1) | 63.5 (6.8) | 66.9 (5.5) | 61.4 (5.7) | 70.5 (5.0) | 65.5 (5.1) | 67.5 (5.5) | 53.0 (7.1) | 62.8 (5.2) | 58.3 (4.9) | 63.6 (5.1) | 63.8 (6.1) | 62.0 (5.1) |
| Smoke (seemed/did not seem) harsh | 67.5 (6.0) | 55.0 (6.7) | 55.8 (7.3) | 61.1 (7.0) | 61.4 (6.9) | 53.8 (7.3) | 55.0 (6.6) | 56.1 (5.9) | 58.2 (6.6) | 45.2 (7.1) | 51.5 (6.9) | 53.7 (6.8) | 54.8 (6.9) | 51.3 (5.7) | 55.5 (7.0) |
| (Did not leave/Left) a good aftertaste in my mouth | 46.6 (5.8) | 50.3 (6.8) | 50.2 (6.2) | 48.5 (6.8) | 52.2 (6.5) | 46.7 (6.5) | 46.4 (6.5) | 44.7 (5.9) | 50.2 (6.7) | 21.9 (4.7) | 32.3 (4.9) | 32.0 (5.4) | 34.0 (5.1) | 32.2 (5.4) | 32.0 (4.8) |
| Somehow it (seemed/did not seem) stale | 78.5 (5.7) | 72.5 (7.1) | 76.6 (6.2) | 76.9 (5.8) | 82.2 (5.1) | 79.3 (5.3) | 78.3 (5.7) | 78.1 (5.7) | 78.1 (5.9) | 53.5 (8.1) | 71.8 (6.4) | 68.6 (6.9) | 73.3 (6.6) | 72.0 (6.4) | 72.8 (6.9) |
| Smoke seemed (very weak/very strong) | 58.5 (5.4) | 62.5 (4.8) | 59.8 (5.5) | 49.7 (6.3) | 65.0 (5.5) | 64.9 (5.1) | 68.2 (4.2) | 64.4 (5.1) | 61.9 (5.6) | 47.8 (6.7) | 49.6 (5.2) | 56.3 (5.3) | 58.3 (5.5) | 57.5 (4.3) | 55.0 (5.2) |
| Smoke smell: (unpleasant/pleasant) | 49.7 (5.2) | 49.5 (6.5) | 51.3 (5.3) | 55.5 (5.8) | 51.5 (5.5) | 49.5 (6.0) | 51.9 (5.9) | 49.7 (5.6) | 53.9 (5.9) | 37.8 (5.0) | 40.6 (5.2) | 38.0 (5.8) | 45.5 (6.0) | 40.9 (6.1) | 39.4 (5.9) |