Table 3.
Accuracy of gene signatures that predict FDG uptake features in study cohorta
Predicted FDG uptake feature | Accuracyb | Meta-genes (n) | Genes (n) |
---|---|---|---|
pSUVmax | 0.774 | 15 | 508 |
pSUVmean | 0.765 | 13 | 428 |
pSUVmedian | 0.748 | 13 | 428 |
pSUVmin | 0.762 | 18 | 612 |
pSUV90% | 0.765 | 16 | 552 |
PSUV75% | 0.777 | 14 | 458 |
pSUVsigma | 0.765 | 16 | 555 |
pSUVvariance | 0.804 | 12 | 387 |
pSUVskew | 0.784 | 14 | 516 |
pSUVkurtosis | 0.725 | 18 | 589 |
pSUVarea | 0.866 | 11 | 300 |
pSUVpoints | 0.875 | 10 | 270 |
pSUVMTV | 0.871 | 10 | 270 |
pSUVTGV | 0.854 | 11 | 315 |
pSUVPCA1 | 0.793 | 13 | 458 |
pSUVPCA2 | 0.765 | 16 | 473 |
Predicted features are denoted with a prefix “p” and are based on a linear combination of genes from the study cohort (see Methods)
Accuracy defined as 1- Σ25 |pFDGfeaturex-FDGfeaturex|/Δrange.12