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. 2010 May;24(3):169–180. doi: 10.1016/S1674-8301(10)60026-7

Table 1. Gene symbols (and aliases) defining the molecular signature of VSMC.

Gene name Function
MYH11 (smooth muscle myosin heavy chain) Contractile
MYLK_v7 (telokin) Contractile
ACTA2 (smooth muscle alpha actin) Contractile
CNN1 (smooth muscle calponin) Contractile
TPM1 (alpha tropomyosin) Contractile
TPM2 (beta tropomyosin) Contractile
CALD_v1 (heavy caldesmon) Contractile
MYLK_v6 (smooth muscle myosin light chain kinase) Contractile
ACTN1 (alpha actinin) Contractile
ACTG2 (smooth muscle gamma actin) Cytoskeleton
SMTNA (smoothelin A) Cytoskeleton
SMTNB (smoothelin B) Cytoskeleton
VCL_v1 (meta-vinculin) Cytoskeleton
DMD (dystrophin) Cytoskeleton
TAGLN (Sm22 alpha) Cytoskeleton
APEG1 (SPEG complex locus) Cytoskeleton
DES (desmin) Cytoskeleton
ITGA8 (alpha 8 integrin) Cytoskeleton
ITGA1 (alpha 1 integrin) Cytoskeleton
HEY2 (CHF-1) Transcription
BARX2b Transcription
MYOCD (myocardin) Transcription
SRF (serum response factor) Transcription
AEBP1 (ACLP) Transcription
HDAC8 (histone deacetylase 8) Transcription
PTK2 (FRNK) Signaling
NOTCH3 Signaling
ELN (elastin) Structural
LPP (lipoma preferred partner) Protein binding
GLMN (glomulin) Protein binding
CSRP1 (CRP1) Protein binding
PGM5 (phosphoglucomutase) Metabolism
HRC (histine-rich calcium binding protein) Calcium binding
KCNMB1 (maxi-K beta 1 subunit) Ion channel