Table 1. Main characteristics of studies included in this meta-analysis.

First author (reference)	Year	Country	Ethnicity	Cases	Controls	Controls
						PHWE*	Frequency of C allele
Wadelius(11)	1999	Sweden	European	178	160	0.137	0.438
Lunn(12)	1999	USA	European	96	159	0.811	0.343
Lunn(12)	1999	USA	African	12	8	0.719	0.313
Habuchi(13)	2000	Japan	Asian	252	131	0.545	0.512
Gsur(14)	2000	Austria	European	63	126	0.087	0.361
Chang(15)	2001	USA	European	225	182	0.435	0.360
Kittles(16)	2001	USA	African	71	111	0.932	0.297
Haiman(17)	2001	USA	European	590	782	0.118	0.386
Yamada(18)	2001	Japan	Asian	101	200	0.002	0.445
Latil(19)	2001	France	European	226	156	0.198	0.423
dos Santos-1(20)	2002	Brazil	European	84	128	0.221	0.344
dos Santos-2(20)	2002	Brazil	African	8	72	0.383	0.340
Stanford-1(21)	2002	USA	European	560	523	0.592	0.396
Stanford-2(21)	2002	USA	European	30	15	0.985	0.367
Tigli(22)	2003	Turkey	Asian	92	73	0.375	0.356
Lin CC(23)	2003	China	Asian	93	121	0.018	0.636
Madigan(24)	2003	China	Asian	174	274	0.222	0.608
Cicek-1(25)	2004	US	European	397	436	0.609	0.399
Cicek-2(25)	2004	US	African	38	38	0.165	0.329
Vesovic(26)	2005	Germany	European	174	89	0.095	0.393
Forrest(27)	2005	UK	European	262	462	0.348	0.359
Antognelli(28)	2005	Italy	European	384	360	0.058	0.444
Okugi(29)	2006	Japan	Asian	102	117	0.751	0.470
Yang(30)	2006	China	Asian	163	202	0.541	0.589
Sobti(31)	2006	India	Asian	100	100	0.634	0.300
Gunes(32)	2007	Turkey	Asian	148	102	0.713	0.284
Hamada(33)	2007	US	European	222	83	0.441	0.386
Cussenot(34)	2007	France	European	998	777	0.105	0.407
Onen(35)	2007	Turkey	Asian	100	105	0.910	0.433
Sobti(36)	2008	Indian	Asian	157	170	0.007	0.312
Sarma(37)	2008	US	African	126	322	0.000	0.387

*HWE: Hardy-Weinberg equilibrium