Table 1. Primary information on five tSNPs of the TGF-β1 gene among the CWP cases and controls.
No. | SNP ID | Base Change | Positiona | Location | MAF(%) |
P-valueb | P -value for HWEC | |
Case | Control | |||||||
1 | rs1800469 | C > T | 14128514 | Promoter | 0.49 | 0.48 | 0.581 | < 0.001 |
2 | rsl800470 | T > C | 14127139 | Exon 1 | 0.43 | 0.48 | 0.018 | < 0.001 |
3 | rs2241716 | G > A | 14122304 | Intron 2 | 0.36 | 0.36 | 0.927 | 0.059 |
4 | rs4803455 | C > A | 14119727 | Intron 2 | 0.05 | 0.05 | 0.494 | 0.252 |
5 | rs11466345 | A > G | 14111679 | Intron 5 | 0.33 | 0.28 | 0.015 | 0.044 |
a SNP position in NCBI dbSNP; bP value for allele distribution difference between case and control; cHWE (Hardy-Weinberg equilibrium) P value in the control group.