Table 5. Stratification analysis between the genotypes of SNP2 rs1800470 polymorphism and CWP risk.
Variables | Case/control | Case [n(%)] |
Control [n(%)] |
P | OR (95% CI) | Adjusted OR(95% CI)a | ||
TT/CT | CC | TT/CT | CC | |||||
Total | 508/526 | 461(90.75) | 47(9.25) | 441(83.84) | 85 (16.16) | 0.012 | 0.53(0.36-0.77) | 0.54(0.37-0.79) |
Exposure period(y) | ||||||||
<28 | 221/223 | 199(90.04) | 22(9.96) | 185(82.96) | 38(17.04) | 0.032 | 0.54(0.31-0.94) | 0.54(0.31-0.95) |
≥28 | 287/303 | 262(91.29) | 25(8.71) | 256(84.49) | 56(15.51) | 0.034 | 0.52(0.31-0.87) | 0.56(0.32-0.96) |
Smoking status | ||||||||
Never | 289/324 | 265(91.70) | 24(8.30) | 264(81.48) | 60(18.52) | 0.003 | 0.40(0.24-0.66) | 0.40(0.24-0.66) |
Ever | 219/202 | 196(89.50) | 23(10.50) | 177(87.62) | 25(12.38) | 0.713 | 0.83(0.46-1.52) | 0.89(0.48-1.67) |
Stage | ||||||||
I | 237/526 | 211(89.03) | 26(10.97) | 441(83.84) | 85(16.16) | 0.230 | 0.91(0.56-1.16) | 0.80(0.56-1.15) |
II | 216/526 | 200(96.59) | 16(7.41) | 441(83.84) | 85(16.16) | 0.004 | 0.42(0.24-0.73) | 0.41(0.22-0.76) |
III | 55/526 | 50(90.91) | 5(9.09) | 441(83.84) | 85(16.16) | 0.172 | 0.52(0.20-1.34) | 0.50(0.18-1.36) |
a Adjusted for age, smoking and exposure period.