Table 6. Stratification analysis between the genotypes of SNP5 rs11466345 polymorphism and CWP risk.
| Variables | Case/control | Case [n(%)] |
Control [n(%)] |
P | OR (95% CI) | Adjusted OR(95% CI)a | ||
| AA/AG | GG | AA/AG | GG | |||||
| Total | 508/526 | 455(89.57) | 53(10.43) | 495(94.11) | 31(5.89) | 0.002 | 1.86(1.17-2.95) | 2.17(1.34-3.51) |
| Exposure period(y) | ||||||||
| <28 | 221/223 | 201(90.95) | 20(9.05) | 213(95.92) | 10(4.48) | 0.034 | 2.12(0.97-4.64) | 2.31(1.04-5.12) |
| ≥28 | 287/303 | 254(88.50) | 33(11.50) | 282(93.07) | 21(6.93) | 0.034 | 1.74(0.98-3.09) | 2.08(1.12-3.87) |
| Smoking status | ||||||||
| Never | 289/324 | 244(84.43) | 45(15.57) | 310(95.68) | 14(4.32) | < 0.001 | 4.08(2.19-7.61) | 4.74(2.49-9.00) |
| Ever | 219/202 | 211(96.35) | 8(3.65) | 185(91.58) | 17(8.42) | 0.049 | 2.42(1.02-5.74) | 2.49(1.00-6.20) |
| Stage | ||||||||
| I | 237/526 | 209(88.19) | 28(11.81) | 495(94.11) | 31 (5.89) | 0.005 | 2.14(1.25-3.66) | 2.18 (1.27-3.74) |
| II | 216/526 | 193(89.35) | 23(10.65) | 495(94.11) | 31(5.89) | 0.019 | 1.90(1.08-3.35) | 2.16 (1.13-4.12) |
| III | 55/526 | 53(96.36) | 2(3.63) | 495(94.11) | 31(5.89) | 0.671 | 1.66(0.39-7.13) | 1.39 (0.31-6.28) |
aAdjusted for age, smoking and exposure period.