Fig. 2.

Double-staining of (pro)renin receptor mRNA as detected by in situ hybridization and of pituitary hormones as detected by immunohistochemistry. Cells presenting both (pro)renin receptor mRNA signal (purple) and GH immunoreaction (brown) are indicated (a, asterisks). (Pro)renin receptor mRNA-negative GH cells can also be seen (a, arrows). (Pro)renin receptor mRNA is coexpressed in some ACTH cells (b, asterisks). (Pro)renin receptor mRNA-negative ACTH cells could be seen (b, arrows). (Pro)renin receptor mRNA is expressed in a few prolactin cells (c, asterisks) and TSH cells (d, asterisk). (Pro)renin receptor mRNA was not expressed in LH cells (e). Bar=10 µm