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. 2013 Feb 25;168(6):1375–1387. doi: 10.1111/bph.12042

Figure 2.

Figure 2

Expression of CCX-CKR impairs CXCR3-dependent migrationHEK293 expressing stable hCXCR3 migrated towards various concentration of CXCL10 whereas migration of HEK293 expressing hCXCR3+hCCX-CKR was abolished (A). The same migratory behavior was observed with various concentrations of CXCL9, another CXCR3 ligand (B). HEK293 stably expressing hCXCR3+hCX3CR1 show migratory behaviour towards various concentration of CXCL10 or CX3CL1 (C). Data represent the means ± SEM of three independent experiments. Statistical significance was tested by means of multiple comparison anova and Tukey's post hoc analysis. Asterisks indicate P ≤ 0.05.