Table 2. Genotype and allele frequencies of the CASP8 -652 6N ins/del polymorphism among cases and controls and their associations with risk of prostate cancer.
CASP8 | Cases (n = 406) |
Controls (n = 408) |
Adjusted OR (95% CI)a | Pb |
n (%) | n (%) | |||
Genotypes | 0.001 | |||
ins/ins | 257 (63.3) | 211 (51.7) | 1.00 | |
ins/del | 132 (32.5) | 159 (39.0) | 0.68 (0.51-0.92) | 0.011 |
del/del | 17 (4.2) | 38 (9.3) | 0.34 (0.19-0.63) | 0.001 |
del allele | 0.20 | 0.29 | < 0.001 | |
Ptrend | 0.001 |
a Adjusted for age, smoking and drinking status; b Two-sided χ2 test. OR: odds ratio.