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. 2011 Mar;25(2):135–140. doi: 10.1016/S1674-8301(11)60017-1

Fig. 5. Inhibition of miR-141 restores PTEN levels.

Fig. 5

HaCaT cells were transfected with miR-141 inhibitors and treated with 30 mJ/cm2 UVB. PTEN, p-AKT and Bcl-xL expression were assessed by Western blotting 24 h after UVB irradiation. Equal amounts of total cellular protein were resolved by 10% SDS-PAGE, and β-actin was used as an internal control. Lane 1: untreated control group; Lane 2: UVB treated group; Lane 3: UVB+ anti-miR-141 negative control group; Lane 4: UVB+ anti-miR-141 group.