Table 1. Variations in mtDNA identified in the subjects.

Genetype	Nucleotide change	Amino acid change	Mutation type	Category	Patients (n)		Controls (n)
					Homo-plasmy	Heteio-plasmy	Homo-plasmy	Heteio-plasmy
Mitochondrial	709G>A	12SrRNA	Missense	undefined	3	0	2	0
	752C>T	12SrRNA	Missense	polymorphism	4	0	1	0
	827A>G	12SrRNA	Missense	pathogenic	6	0	0	0
	961T>C	12SrRNA	Missense	pathogenic	2	0	0	0
	1005T>C	12SrRNA	Missense	polymorphism	6	0	3	0
	1048C>T	12SrRNA	Missense	polymorphism	2	0	0	0
	1095T>C	12SrRNA	Missense	pathogenic	1	0	0	0
	1119T>C	12SrRNA	Missense	polymorphism	3	0	0	0
	1382A>G	12SrRNA	Missense	polymorphism	4	0	3	0
	1438A>G	12SrRNA	Missense	polymorphism	125	0	112	0
	1555A>G	12SrRNA	Missense	pathogenic	2	0	0	0
	7445A>G	tRNASer(UCN)	Missense	pathogenic	0	0	0	0
	7472insC	tRNASer(UCN)	Missense	pathogenic	0	0	0	0
	7511T>C	tRNASer(UCN)	Missense	pathogenic	0	0	0	0
Subtotal					158	0	121	0
DM subtotal					11		0

DM: definite deafening mutations.