. 2012 Apr 16;26(4):253–259. doi: 10.7555/JBR.26.20110122

Table 2. Stratified analyses of the hsa-mir-499 rs3746444 polymorphism on cancer risk.

Variables	n^a	Cases/controls	G vs A			GG vs AA			AG vs AA
Variables	n^a	Cases/controls	OR(95%CI)	P^b	I²(%)	OR(95%CI)	P^b	I²(%)	OR(95%CI)	P^b	I²(%)
Total	10	6,134/7,141	1.07(0.98-1.17)^c	0.037	49.7	1.11(0.94-1.30)	0.473	0.0	1.14(0.97-1.34)^c	0.000	74.3
Cancer type
Breast cancer	3	2,588/3,260	1.10(1.00-1.20)	0.114	53.9	1.19(0.93-1.53)	0.124	52.0	1.09(0.97-1.22)	0.327	10.6
Other cancer	7	3,546/3,881	1.02(0.94-1.11)	0.057	51.0	1.05(0.85-1.29)	0.698	0.0	1.20(0.93-1.55)^c	0.000	81.5
Ethnicity
Asian	4	2,845/3,134	1.15(0.98-1.36)^c	0.042	63.4	1.30(0.99-1.72)	0.254	26.2	1.18(0.92-1.51)^c	0.007	75.3
Caucasian	6	3,289/4,007	1.00(0.93-1.08)	0.310	16.1	1.01(0.83-1.24)	0.780	0.0	1.13(0.90-1.41)^c	0.001	76.9
Source of controls
PB	3	2,297/2,358	1.12(1.00-1.25)	0.062	64.0	1.36(0.99-1.88)	0.192	39.4	1.08(0.95-1.23)	0.309	14.7
HB	7	3,837/4,783	1.03(0.95-1.10)	0.096	44.3	1.03(0.85-1.24)	0.776	0.0	1.19(0.94-1.50)^c	0.000	81.6

HB: hospital-based of control; PB: population-based of control. ^aNumber of comparisons. ^bP value of Q-test for heterogeneity test. ^cRandom-effects model was used when P value for heterogeneity test <0.05; otherwise, fix-effects model was used.