Fig. 1. Representative cresyl violet-stained coronal sections of the hippocampus from rats (×400).
Dementia in rats was induced with D-galactose. The rats were then treated with Ginkgo biloba leaf extract as detailed in Materials and Methods. A: Control group; B: D-galactose (Gal) group; C: EGB-L group; D: EGB-M group; E: EGB-H group; F: Therapy group. Normal arrangement and number of cells are seen in the hippocampus of the control group. The sections of the Gal group and treatment group show many cells with pyknotic nuclei and cytoplasm and they are deranged, especially for the Gal group. The sections from the groups of EGB-L and EGB-M demonstrate fewer cells with pyknotic nuclei and cytoplasm. Cells from the EGB-H group are identical to control, except for several deranged cells.