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. 2012 Dec 19;27(1):51–55. doi: 10.7555/JBR.27.20120048

Fig. 3. Induction of HIF-1α mRNA expressions in U87MG cells by ATRA.

Fig. 3

A: HIF-1α mRNA expression in U87 glioma cells. B: HIF-1α mRNA expression in SHG44 glioma cells. ATRA can significantly increase the expression of HIF-1α mRNA in glioma cells. The difference between the 5 µmol/L ATRA group and the 10 µmol/L ATRA group in SHG44 glioma cells was statistically significant. But there was no significant difference between the 5 µmol/L ATRA group and the 10 µmol/L ATRA group in U87 glioma cells (**P < 0.01).