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. 2013 Mar 14;3:1452. doi: 10.1038/srep01452

Figure 1. Scheme of the TIRF based approach.

Figure 1

(a) Schematic illustration of the detection principle. Fluorescently labeled liposomes containing Lex-GSLs interact with an SLB containing Lex-GSL. TIRF-based illumination is used to track surface-bound liposomes. (b) Chemical structure of lipids used. (c) A typical TIRF image of surface bound liposomes together with a kymograph and the intensity profile of a small image area containing a single liposome.