Figure 6. Protein sequence homology alignment of Tm isoforms among various species.
The α– and β–Tm isoforms presented here are detected in pig, mouse and human, encoded by TPM1 and TPM2 genes. Highlighted areas marked in purple and green indicate amino acid substitutions between α–Tm and β–Tm across differen species, respectively. Asterisks indicate the conserved sequence regions. A1X899_PIG is encoded by TPM2 gene but the sequence is marked as “unreviewed” in the Swiss-Prot database.