Table 2.
Patients with grade 3 or 4 toxicity by the NCI Common Toxicity Criteria version 3.0.
| Characteristics | FLOX arm | 3-week arm | P value | ||
|---|---|---|---|---|---|
| Grade III | Grade IV | Grade III | Grade IV |
||
| Diarrhea | 4 (16%) | 1 (4%) | 4 (16%) | 1 (4%) | .11 |
| Dehydration | 2 (8%) | — | 1 (4%) | — | .09 |
| Nausea | 1 (4%) | — | 2 (8%) | — | .101 |
| Vomiting | 3 (12%) | — | 1 (4%) | — | .07 |
| Stomatitis | 1 (4%) | — | 1 (4%) | — | — |
| Hematological | |||||
| Neutropenia | 1 (4%) | 1 (4%) | — | — | |
| Anaemia | 2 (8%) | 1 (4%) | — | .089 | |
| Thrombocytopenia | — | — | — | ||
| Neurosensory | 1 (4%) | — | 1 (4%) | — | — |
| Thrombosis and embolism | 1 (4%) | — | 1 (4%) | — | — |
| Liver | |||||
| Elevated transaminases | 2 (8%) | — | 3 (4%) | — | .21 |