Table 1.
Patient | Age (years) | Gender | Treatment | Pre-/posttherapy BM involved, % | Pre-/posttherapy MYD88 L265P levels | Change in BM involved, % | Change in MYD88 L265P levels, % |
---|---|---|---|---|---|---|---|
A | 61 | Male | Benda-R | 70 (negative) | 78.45 (negative) | −100 | −100 |
B | 44 | Male | R-CD | 90 | 60.73 | −89 | −96.33 |
10 | 2.23 | ||||||
C | 52 | Male | R-CD | 50 | 72.12 | −90 | −73.61 |
5 | 19.03 | ||||||
D | 59 | Male | Everolimus | 95 | 99.15 | −47 | −45.39 |
50 | 54.15 | ||||||
E | 63 | Male | Everolimus | 90 | 96.07 | −67 | −21.03 |
30 | 75.87 | ||||||
F | 70 | Male | Everolimus | 95 | 95.93 | −37 | −8.61 |
60 | 87.67 | ||||||
G | 63 | Male | Everolimus | 20 | 67.93 | 25 | 12.87 |
25 | 76.67 |
Changes in expression levels for MYD88 L265P were calculated from a standard curve.
Benda-R, bendamustine and rituximab; R-CD, rituximab, cyclophosphamide, and dexamethasone.