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. 2012 Sep 11;6(2):503–507. doi: 10.1242/dmm.010587

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© 2013. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 1. — Postnatal maturation of cardiac electrical conduction. (A-H) Sequential ECG in a cohort of neonatal mice revealed increase in heart rate (A), decrease in QRS duration (B), QTc (C) and QT dispersion (D) in the hours after birth. P values in A, B and D indicate the first point at which parameters become significantly different from immediate postnatal values (two-tailed t-test; n=8). Error bars show s.e.m. The trends noted in the first 24 hours continued over the 10 days following birth (E,F,G,H).