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Incidence rate of severe hypoglycemia by insulin regimen. Gray = severe hypoglycemia requiring assistance of another person for oral treatment. Black = severe hypoglycemia resulting in seizure or coma. Incidence rates for all severe hypoglycemia are shown above each bar. All severe hypoglycemia: *NPH vs. CSII, p=.04. Severe hypoglycemia resulting in seizure/coma: †CSII vs. NPH, p=.004; ‡CSII vs. B-B, p=.05.
