Table 3.

Multivariate analysis for progression to keratoconus related VK indices by the mixed model

	CK		I-S		KISA
	Coefficient†	P	Coefficient	P	Coefficient	P
FH* vs Controls	0.005	0.52	0.008	<0.001	0.002	0.48
FH vs FL*	0.017	0.009	0.007	<0.001	−0.004	0.15

^*FH: keratoconus relatives with high risk (age<30 or Central K>=47.2 or I-S >=1.2 or KISA>=60), other relatives were defined as low risk, i.e. FL

^†Interaction term of centered age by group, which indicated the difference of progression rate.