Table 1. Association between the IGF2 gene methylation and sex, age and selected factors in transitional cell carcinoma (TCC) patients.
| Variables | Cases(n) | Frequency of hypomethylation[n (%)] |
|
| TCC tissues | Normal bladder tissues | ||
| Sex | |||
| Male | 81 | 21(25.9) | 8(9.9) |
| Female | 44 | 13(29.5) | 6(13.6) |
| P value | 0.664 | 0.561 | |
| Age (years) | |||
| <60 | 49 | 12(24.5) | 8(16.3) |
| ≥60 | 76 | 22(28.9) | 6(7.9) |
| P value | 0.585 | 0.144 | |
| Tobacco smoking | |||
| Never | 68 | 20(29.4) | 8(11.8) |
| Ever | 57 | 14(24.6) | 6(10.5) |
| P value | 0.544 | 0.827 | |
| Alcohol drinking | |||
| Never | 71 | 21(29.6) | 8(11.3) |
| Ever | 54 | 13(24.1) | 6(11.1) |
| P value | 0.493 | 0.978 | |
| Green tea drinking | |||
| Never | 77 | 23(29.9) | 10(13.0) |
| Ever | 48 | 11(22.9) | 4(8.3) |
| P value | 0.395 | 0.422 | |
Smoking is the inhalation of the smoke of burning tobacco that is used mostly in three forms: cigarettes, pipes, and cigars. Alcohol is consumed largely for their physiological and psychological effects. The two items were divided into never and ever according to their histories. P values for Fisher's exact test.