Table 2.

eighborhood variation in the effect of APOE-E4 genotype on change in cognitive functioning: multilevel regression estimates (standard error).

	Model 1	Model 2
Intercept	−290*** (.021)	−290*** (.021)
Baseline cognitive function	−.170*** (.016)	−.171*** (.016)
APOE-E4 genotype	−.123*** (.024)	−.125*** (.023)
Neighborhood disorder	−.415*** (.106)	−.468*** (.107)
Neighborhood disadvantage	−.004 (.019)	−.004 (.019)
Respondent race [Black = 1]	.040 (.031)	.038 (.031)
Respondent education (std.)	.019* (.009)	.018* (.009)
Respondent age (std.)	−.256*** (.011)	−.257*** (.011)
Respondent sex [Male= 1]	.004 (.016)	.005 (.016)
Duration of residence	.051*** (.009)	.050*** (.009)
Follow-up time	−.057*** (.009)	−.057*** (.009)
APOE-E4 * Disorder		.371** (.139)
SD (slope)	.071	.066
−2LL	5934.774	5933.274
Likelihood ratio	8.542	1.500
df	1	1
p <	.003	.220

Note: all data have been weighted to correct for sampling design of the Chicago Health and Aging Project. The full sample models include a random effect for APOE-E4 genotype at the neighborhood-level. The likelihood ratios compare the -2LogLikelihood estimates of the current model to the prior baseline model. Corresponding degrees of freedom and probability of overall model improvement are provided.

^***p <.001,

^**p <.01,

^*p <.05.