Table 3.

Association between APOE-E4 genotype and cognitive decline by neighborhood disorder.

	Level of neighborhood social disorder
	Low	High
Intercept	−.308*** (.039)	−.187*** (.049)
Baseline cognitive function	−.174*** (.030)	−.169*** (.019)
APOE-E4 Genotype	−.186*** (.027)	−.083*** (.021)
Neighborhood disadvantage	−.087** (.030)	−.080 (.045)
Respondent race [Black = 1]	.086 (.046)	−.038 (.042)
Respondent education (std.)	−.027 (.015)	.033** (.012)
Respondent age (std.)	−.293*** (.015)	−.245*** (.015)
Respondent sex [Male = 1]	.063* (.025)	−.027 (.022)
Duration of residence	.045*** (.011)	.064** *(.013)
Follow-up time	−.057*** (.013)	−.053*** (.012)
−2LL	2532.806	3362.590
Likelihood ratio	12.230	2.872
df	1	1
p <	.000	.090

Note: all data have been weighted to correct for sampling design of the Chicago Health and Aging Project. Cell entries denote random intercepts models that capture differences in the mean level of cognitive function across neighborhoods. A random slope for APOE-E4 genotype is not estimated in these models. The likelihood ratios compare the -2LogLikelihood estimates of the current model to the prior baseline model. Corresponding degrees of freedom and probability of overall model improvement are provided.

^***p < .001,

^**p < .01,

^*p < .05.