Table 1.
Descriptive statistics at baseline evaluation for incident dementia cases, participants who remained non-demented, and total sample
| Remained non- demented (n=457) | Incident dementia (n=46) | Total sample (n=503) | Statistics | ||
|---|---|---|---|---|---|
| Age at baseline (mean ± SD years) | 79.41±5.12 | 82.15±5.55 | 79.66±5.20 | t(501)=3.434, p=0.001 | |
| Education (mean ± SD years) | 11.12±4.86 | 7.70±5.01 | 10.58±4.37 | t(499)=4.537, p<0.001 | |
| Race/Ethnicity | % White/other | 30.2 | 21.7 | 29.6 | χ2(2)=7.083, p=0.029 |
| % African American | 33.2 | 21.7 | 32.1 | ||
| % Hispanic | 36.5 | 56.5 | 38.3 | ||
| APOE ε4 frequency | 24.4 | 22.7 | 24.3 | χ2(1)=0.062, p=0.803 | |
| Vascular risk factors | % Diabetes mellitus | 21.0 | 23.9 | 21.3 | χ2(1)=0.211, p=0.646 |
| % Hypertension | 69.1 | 65.2 | 68.8 | χ2(1)=0.301, p=0.584 | |
| % Heart disease | 22.5 | 17.4 | 22.1 | χ2(1)=0.644, p=0.422 | |
| % Stroke | 9.8 | 15.2 | 10.3 | χ2(1)=1.300, p=0.254 | |
| Vascular history score (median) | 1 | 1 | 1 | Mann-Whitney U = 10242.50, p=0.761 | |
| Time between MRI scan and baseline evaluation (mean ± SD months) | 0.96±5.27 | 1.61±7.05 | 0.79±6.25 | t(499)=0.766, p=0.444 | |
| Time between MRI scan and follow-up visit (mean ± SD months) | 40.18±9.68 | 41.63±10.69 | 40.28±9.77 | t(474)=0.911, p=0.363 | |
| Regional WMH volume (mean ± SD cm3) | Frontal | 1.69±3.19 | 2.04±2.84 | 1.70±3.16 | Diagnostic Group: F(1,441)=0.258, p=0.612), Group by Region: F(3,1323)=0.534, p=0.659) |
| Temporal | 0.12±0.28 | 0.13±0.23 | 0.12±0.27 | ||
| Parietal | 1.24±2.48 | 1.77±2.55 | 1.29±2.49 | ||
| Occipital | 0.16±0.38 | 0.13±0.17 | 0.15±0.37 | ||
| Relative hippocampus volume | 0.29±0.06 | 0.28±0.07 | 0.29±0.06 | F(1,435)=0.339, p=0.561 | |