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HK-II expression in comparison with pimonidazole distribution. Representative images of (a) pimonidazole and (b) HK-II IHC staining. Typical immunostaining of pimonidazole in (c) Pimo+ and (d) Pimo−. (e) HK-II expression assessed by semiquantitative analysis in Pimo+ and Pimo−. N, necrotic/apoptotic regions.
