Figure 5. Axis analysis of the Snyderome.

19 sequential RNA-Seq profiles were mined for BIT Axis scores, which are plotted relative to sampling day for the individual described in [20]. P-values indicate the signifcance associated with t-test comparison of high blood glucose versus normal (Axes 1, 5 and 6) or the comparison of acute phase of viral infection - Days 0, 290 and 292 - versus the remainder. Colors indicate the phases of human rhinovirus infection (HRV; blue), recovery (yellow), respiratory syncitial virus infection (RSV; green), and pre-diabetes/high blood glucose (red). The green triangle corresponds to a spike in cytokine profile at day 301, which does not obviously impact the Axes. The RSV had not yet cleared at days 307 and 311 when the pre-diabetic state first became apparent, so these points are shown in green and red. The other Axes did not show significant changes.