Skip to main content
. 2013 Mar 14;9(3):e1003215. doi: 10.1371/journal.ppat.1003215

Table 2. In vivo blockade of PD-L2, but not PD-L1, results in a reduced incidence of Mf within the blood and pleural cavity.

Incidence of blood Mf Incidence of PC Mf
IgG αPD-L1 αPD-L2 αPD-L1 + αPD-L2 IgG αPD-L1 αPD-L2 αPD-L1 + αPD-L2
Exp 1 3/6 3/3 1/6 2/5 4/6 3/3 1/6 1/5
Exp 2 3/6 5/6 1/6 2/5 3/6 4/5 4/6 3/5
Exp 3 5/8 5/7 4/7 3/7 7/8 7/7 4/7 3/7
Total 11/20 13/16 6/19* 7/17* 14/20 14/15 9/19* 7/17*
(55%) (81%) (32%) (41%) (70%) (93%) (47%) (41%)
*

Significant difference in Mf incidence driven by αPD-L2 treatment, p<0.001 (GLM using combined data from three experiments).