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. 2013 Mar 14;9(3):e1002953. doi: 10.1371/journal.pcbi.1002953

Figure 8. Validation of the model.

Figure 8

(A) 2AG production is not altered by 10 µM BAPTA included in the simulation, which is consistent with the observation that 10 µM BAPTA does not block 20 Hz LTD. (B) The PKC inhibitor chelerythrine (Che) blocks LTP induced by theta burst stimulation (TBS) but does not produce a non-specific decay in the field population spike in striatal slices.