Table II.

Univariate and multivariate analysis of clinicopathological parameters associated with T/N ratio of KAP in HCC.

Factors	Groups	Pt. no. (Mean ± SD)	KAP T/N ratio (95% CI)	Unadjusted β (95% CI)	Adjusted β
Gender	Male	90	1.05±0.89	0.28 (−0.09, 0.65)
	Female	27	0.77±0.71
Age (years)	>54	62	0.90±0.81	−0.19 (−0.50, 0.12)
	≤54	55	1.09±0.91
Cirrhosis	Yes	48	1.03±0.99	0.74 (−0.25, 0.39)
	No	69	0.96±0.76
HBsAg	Positive	80	1.02±0.86	0.11 (−0.22, 0.45)
	Negative	37	0.91±0.85
Anti-HCV	Positive	31	1.10±1.05	0.15 (−0.21, 0.50)
	Negative	86	0.95±0.78
Microvascular invasion	Yes	39	1.12±1.00	0.21 (−0.13, 0.54)
	No	78	0.92±0.77
Macrovascular invasion	Yes	9	1.26±0.75	0.30 (−0.29, 0.89)
	No	108	0.97±0.86
Edmondson's histological grading	>II	87	0.94±0.83	−0.19 (−0.55, 0.17)
	≤II	30	1.13±0.93
Capsule	Yes	86	0.95±0.75	−0.16 (−0.52, 0.19)
	No	31	1.11±1.10
Microsatellite lesions	Yes	20	1.25±0.88	0.32 (−0.10, 0.73)
	No	97	0.93±0.85
Tumor number	>1	41	0.95±0.88	−0.95 (−0.43, 0.24)
	1	74	1.04±0.85
Size (cm)	>7.0	37	1.02±0.67	0.01 (−0.33, 0.36)
	≤7.0	77	1.00±0.94
Ascites	Yes	9	1.13±0.76	0.16 (−0.43, 0.75)
	No	108	0.98±0.87
AFP (ng/ml)	>400	31	0.79±0.75	−0.27 (−0.62, 0.09)
	≤400	86	1.06±0.89
AST (U/l)	>100	32	1.30±1.00	0.43 (0.08, 0.77)	0.00 (−0.00, 0.00)a
	≤100	85	0.87±0.77
ALT (U/l)	>80	31	1.18±0.77	0.19 (−0.17, 0.55)
	≤80	86	0.94±0.88
Alcoholism	Yes	36	1.58±0.93	0.86 (0.56, 1.16)	0.87 (057, 1.18)b
	No	81	0.72±0.68
Child-Pugh classification	A	100	0.96±0.82	−0.20 (−0.64, 0.25)
	B	17	1.16±1.06

Pt. no., patient number; HBsAg, hepatitis B surface antigen; anti-HCV, antibody against hepatitis C virus; AFP, α-fetoprotein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CI, confidence interval.

^a0.001 (−0.0003, 0.002); P=0.187;

^bP<0.001.