Table III.
Downregulated proteins in the T47D cells treated with alcohol in comparison to the untreated cells.
| Intensity | ||||
|---|---|---|---|---|
|
|
||||
| Protein | NC | Alcohol | Est'd Z | Accession number |
| SRB7 suppressor of RNA polymerase B homolog (yeast), isoform CRA_a | 7,694.7 | 3,585.2 | 1.4 | EAW96544.1 |
| CD44 molecule (Indian blood group) | 2,125.9 | 1,339.9 | 1.4 | CAC10349.1 |
| G α-q | 8,732 | 3,843.1 | 1.3 | AAB06875.1 |
| β-tubulin | 4,769.7 | 1,569 | 2.4 | AAB59507.1 |
| Keratin, type I cytoskeletal 19 | 21,769.7 | 12,874.6 | 2.4 | P08727.3 |
| Keratin, type I cytoskeletal 19 | 20,520.4 | 2,340.1 | 2.4 | P08727.3 |
| RIN2 protein | 10,761.2 | 3,308.4 | 0.9 | AAI28066.1 |
| Keratin, type I cytoskeletal 19 | 10,293.7 | 2,111.6 | 2.4 | NP_002267.2 |
| β-tubulin | 11,069 | 4,955.7 | 2.4 | AAB59507.1 |
| HMMR protein | 6,474 | 5,410.5 | 1.4 | AAH06984.1 |
| α-amylase | 13,589.9 | 9,157.8 | 2.4 | NP_004029.2 |
| 3-hydroxyisobutyrate dehydrogenase | 1,523.5 | 279.9 | 1.9 | NP_689953.1 |
| Keratin, type II cytoskeletal 79 | 17,336.5 | 12,267.3 | 2.4 | Q5XKE5.1 |
Est'd Z score is a chance value used in ProFound that corresponds to the percentile of the search in a random-match population. For instance, a Z score of 1.65 for a search indicates that the search is in the 95th percentile. NC, untreated control.