Table 2. Summary of IC50 values calculated from MTT assays of ADPs and NPs on BT474 and MDA-MB-231 cells.
| Cell Toxicity MTT Assay of ADPs | ||
| IC50 (µM) | ||
| BT474 (± S.D.) | MDA-MB231 (± S.D.) | |
| ART Dimer Succ. | 0.39 (±0.27) | 32 (±4) |
| ADP106 | 0.06 (±0.03) | 8 (±3) |
| ADP107 | 0.022 (±0.009) | 5 (±2) |
| ADP108 | 0.11 (±0.02) | 3.3 (±0.7) |
| ADP109 | 0.07(±0.01) | 10 (±3) |
| AMPm109 | 1.3 (±0.8) | >>100* |
| NP109 | 0.08 (±0.01) | 7 (±2) |
| NPm109 | 1.3 (±0.4) | >>20* |
Values represent average (±SD) calculated from three independent experiments. *Exceeded maximum concentration of assay.