Table 2. Biodistribution of [111In]67A2 in nude mice bearing SY xenograft.
Day 1 | Day 2 | Day 4 | Day 7 | Day 10 | |
Blood | 17.0±2.8 | 13.7±0.5 | 10.2±0.5 | 4.5±1.6 | 4.4±2.0 |
Lung | 4.2±0.5 | 4.2±0.7 | 3.4±0.7 | 1.6±0.5 | 1.7±0.6 |
Liver | 4.7±0.3 | 4.9±0.7 | 4.1±0.7 | 4.1±1.0 | 2.9±0.4 |
Spleen | 3.5±0.4 | 3.2±0.4 | 2.7±0.4 | 2.4±0.7 | 3.0±0.4 |
Stomach | 0.7±0.3 | 0.8±0.2 | 0.5±0.2 | 0.6±0.3 | 0.4±0.1 |
Intestine | 1.4±0.1 | 1.4±0.1 | 1.1±0.1 | 0.8±0.4 | 0.5±0.1 |
Kidney | 4.9±0.7 | 4.1±0.2 | 3.7±0.2 | 2.2±0.3 | 2.1±0.5 |
Muscle | 1.0±0.2 | 1.0±0.2 | 0.9±0.2 | 0.4±0.1 | 0.5±0.1 |
Bone | 1.5±0.3 | 1.2±0.2 | 1.3±0.2 | 0.8±0.4 | 0.8±0.2 |
Tumor | 15.7±0.9 | 23.8±1.6 | 31.5±7.7 | 18.2±2.2 | 16.7±3.0 |
Data are expressed as decay-corrected % ID/g±SD normalized to a 20-g body weight mouse.