Table 2. Changes of key laboratory parameters pre- and post-artificial liver support system (ALSS) treatment in different subgroups.

Parameters	PE (n = 162)	PE+continuous hemodiafiltration (n = 52)	PE+Plasma perfusion (n = 18)	MARS (n = 15)
TB
Pre-treatment ( µmol/L)	575±174	530±165	558±183	511±137
Post-treatment ( µmol/L)	260±96	253±82	261±95	331±115
Removal rate (%)	55±6	52±5	54±5	34±4
P value	<0.05	<0.05	<0.05	<0.05
Cr
Pre-treatment ( µmol/L)	80±19	301±102	78±15	198±43
Post-treatment ( µmol/L)	76±15	169±52	74±13	145±29
Removal rate (%)	4±5	45±9	4±4	28±4
P value	>0.05	<0.05	>0.05	<0.05
PT
Pre-treatment (s)	32.4±10.3	31.6±8.0	31.2±7.7	28.4±8.4
Post-treatment (s)	20.7±3.6	22.5±6.3	23.6±5.6	30.1±8.8
P value	<0.05	<0.05	<0.05	>0.05

Removal rate was calculated as: (pre-treatment concentration—post-treatment concentration)/pre-treatment concentration.

Abbreviations: PE, plasma exchange; TB, total bilirubin; Cr, creatinine; PT, prothrombin time.