Table 5. MYH9 rs11089788 statistical analysis for a replicate cohort (D) and for the sum of cohorts B and D, that gave statistical significance.

		MYH9 rs11089788			P value, Odds ratio	P value, Odds ratio
Cohort	n	AA	AC	CC	AA+AC vs CC	AA vs AC+CC
D – “Mild”	33	7 (21%)	18 (55%)	8 (24%)	P = 0.024, OR = 3.52 (1.24, 9.97)	P = 0.765, OR = 1.26 (0.37, 4.23)
D – “Severe”	34	6 (18%)	10 (29%)	18 (53%)
B+D – “Mild”	83	23 (28%)	40 (48%)	20 (24%)	P = 0.001, OR = 3.06 (1.54, 6.10)	P = 0.049, OR = 2.26 (0.99, 5.16)
B+D – “Severe”	69	10 (15%)	25 (36%)	34 (49%)

Patients in cohort D belong to families that segregate microscopic hematuria but no known mutation has been found in any of the genes COL4A3, COL4A4, or CFHR5, so far.