Figure 3. Correlating circulating and aortic monocyte counts reveals importance of CCR1 and CCR5 in recruitment of classical monocytes.
- A. Absolute numbers of classical monocytes in aortas of indicated mouse strains after HFD for 8 weeks.
- B,C. Circulating total monocyte (B) and classical monocyte (C) counts in indicated mouse strains after 8 weeks of HFD, as analysed by flow cytometry. All data are expressed as mean ± SD. *Denotes significant differences between groups. n = 15 for each group (One-way ANOVA with Dunnett post hoc test).
- D. Correlation between aortic and circulating classical monocyte counts in indicated mouse strains after 8 weeks of HFD (Pearson correlation).