Figure 2.
— Histologic appearance of the peritoneum in each group. (A) Compared with mice treated with phosphate-buffered saline (PBS) plus 38 μmol/L 3,4-dideoxyglucosone-3-ene (3,4-DGE), mice treated with chlorhexidine gluconate (CG) plus 38 μmol/L 3,4-DGE showed thickened peritoneum. In mice treated with CG+145 μmol/L 3,4-DGE, peritoneal fibrosis was more pronounced. Arrows indicate the submesothelial compact zone (Masson trichrome stain). (B) Thickness of the peritoneal membrane (mean ± standard error of the mean) in mice under various conditions: PBS without 3,4-DGE [PBS+3,4-DGE(-), n = 7]; PBS+38 μmol/L 3,4-DGE (n = 5); PBS+145 μmol/L 3,4-DGE (n = 5); CG+3,4-DGE(-) (n = 5); CG+38 μmol/L 3,4-DGE (n = 6); CG+145 μmol/L 3,4-DGE (n = 5). ** p < 0.01 versus mice treated with PBS and same dose of 3,4-DGE; # p < 0.05; ## p < 0.01.